|
9:00-10:30 |
 |
|
Moderator: |
Dr.
Wolfgang Schoenfeld, CEO, EUCODIS GmbH |
| Panelists: |
| • |
Dr. Simone
Kardinahl, Microbiological Development
and Process Development , Bayer Schering
Pharma AG |
| • |
Dr. Burghard Koenig,
R&D Antiinfectives, Head Biocatalysis,
Sandoz Industrial Products GmbH |
| • |
Dr. Oliver May, Competence
Manager Biocatalysis, DSM Pharmaceutical
Products |
| • |
Dr. Ming-Qiang Zhang,
VP Research, Biotica Technology Limited |
| |
|
|
| Abstract: |
The
use of biocatalytic processes is of
fundamental importance in drug discovery
and production of pharmaceuticals:
Fermentation products - as starting
molecules for further derivatisation
or even final products - are well established
in the industry from its very beginning.
On the other hand, over years the use
of biocatalytic steps to reduce costs
and simplify large scale production
is steadily growing.
However, there is still huge potential
for biocatalytic application in pharmaceutical
research as well as in production, if
the gap can be bridged between high risky,
innovative research using white biotech
tools and low risk, cost driven production
applications.
The panel will discuss the problems and
perspectives of “white” biotech
in “red” biotech:
Do biosynthetic modifications of synthetic
pathways of complex natural compounds
really work as a sustainable platform?
How to bring biocatalysis closer to chemical
catalysis – the cross talk between
chemists and biologists in chemistry?
Competition versus synergy!
How to integrate biocatalytic processes
early during the production development
of novel APIs? |
|
|
|
|
9:00-10:30 |
 |
Moderator: |
Ian
Nicholson, CEO, Chroma Therapeutics |
| Panelists: |
| • |
Joel Besse,
Partner, Atlas Venture |
| • |
Dr. Francesco De Rubertis,
Partner Life Sciences, Index Ventures
Management |
| • |
Dr. Claudio Semeraro,
CEO, Z-Cube srl |
| • |
Dr. Francesco Sinigaglia,
CEO, BioXell |
| |
|
|
| Abstract: |
Factors
such as increasing R&D costs, competition,
regulatory restrictions, access to
patients and public pressure are collectively
increasing the hurdles industry has
to jump in order to bring drugs to
the market in a time and cost effective
manner.
In the past few years, the role
of venture capitalists has morphed
in response to industry developments.
Biotech VCs traditionally invested
in early-stage companies and nursed
them along with advice and connections
(and more cash!) with the intention
of building them into a large drug-discovery
company. Today it appears that this
model is too “capital intensive” and
may no longer be “affordable” by
the venture capital industry.
There is a clear need for innovative
business models in the biotech industry.
Companies are exploring different options
such as asset focused financing and
project financing as alternative solutions
for attractive business models.
Is there really a new business model “under
development”? How can early-stage
companies still attract investments?
What are VCs today seeing as a good
value proposition? This panel will
explore how to finance innovation today. |
|
| |
|
|
|
|
9:00-10:30 |
 |
|
Moderator: |
Dr.
Ruediger Herrmann, Partner, Mayer Brown Rowe & Maw
LLP |
| Panelists: |
| • |
Prof. Gregor Cevc,
CEO, IDEA AG |
| • |
Dr. Rainer Kramer,
VP Business Development, Jerini AG |
| • |
Dr. Holger Reithinger,
Partner, Global Life Science Ventures
GmbH |
| • |
Dr. Christoph Thierolf,
VP Corporate Business Development/M&A,
Fresenius AG |
| |
|
|
| Abstract: |
Licensing
and Strategic Alliances include the potential
for great financial and other benefit to
the parties. However, just as in a perfect
marriage, partners must fit to each other
and be willing to accommodate to the other
and its needs. The closer the relation
the bigger the risks that the alliance
goes sour and that it ends in a painful
winding-up.
The panel will discuss its experiences
of what is necessary for a successful
Licensing and Strategic Alliance and
what needs to be considered for choosing
the right partner and the right form
and structure of a strategic alliance.
In the focus shall be issues such as:
how do I successfully negotiate, where
do cultural differences exist, why is
management of the alliance important
and what differentiates a successful
management from a non-successful, when
is an equity participation a wise tool
and what other forms are recommendable
to make the relationship with the partner “strategic” and
what should be regulated for a situation
of “quarrel” and, even worse,
for “divorce”. The panel
will discuss the topic from all sides
and aspects, including business, financial,
legal and cultural issues.
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|
9:00-10:30 |
 |
Moderator: |
Dr.
Ravi Kiron, President, RK Consulting |
| Panelists: |
| • |
Martina
Molsbergen, VP Business Development,
BioWa, Inc. |
| • |
Dr. Murali K. Prahalad,
Director, Corporate Development, Invitrogen
Corporation |
| • |
Scott Salka , CEO,
Ambit Biosciences |
| • |
Dr. David Sourdive,
COO, Corporate Development, Cellectis
SA |
| |
|
|
| Abstract: |
Many
early-stage biotech companies with
strong discovery platforms often attempt
to commercialize their technologies
before they are market ready. The result
is that they often do not get value
for their innovation and fail to forge
key alliances, are forced to accept
poor terms or simply run out of cash. This
session will examine partnerships with
traditional drug development firms
as well as tools and service companies
as an alternate means of adding value
to a pre-clinical or early-stage portfolio.
The panel features senior executives
from companies with strong platform
technologies that have forged strategic
relationships with a variety of different
firms. They will discuss their strategies
for leveraging these relationships
to build towards commercial success. |
|
|
|
|
| |
|
10:45-11:30 |
• Carola
Schropp, Managing Partner, EBD Group |
| • Filippo
Penati, President, Province of Milan |
| •Ambassador
Umberto Vattani, President, Italian Institute
for Foreign Trade (ICE) |
• |
Dr.
Roberto Gradnik, President of Assobiotec;
Senior Executive VP, Merck Serono International,
Commercial Europe |
• Dr.
Sergio Dompé, President, Farmindustria |
| • James
C. Greenwood, President & CEO, Biotechnology
Industry Organization (BIO) |
• Dr.
Rolf Hoffmann, Senior
VP, Amgen International
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| |
|
11:30-12:30 |
Moderator: |
Roger
Longman, Managing Partner, Windhover Information |
| Panelists: |
| • |
Robert Blum, President & CEO,
Cytokinetics, Inc. |
| • |
Dr. Judith
Hills, Corporate and Business Development,
VP, Licensing, Europe, Japan & Asia
Pacific, Bristol-Myers Squibb |
| • |
Louis Scotti, VP, Marketing
and Business Development, Arena Pharmaceuticals,
Inc. |
| • |
Dr. Rob
Wills, VP, Alliance Management, Johnson & Johnson |
| |
|
|
| Abstract: |
The
upfront cash value of early- and late-stage
biotech alliances, according to data
from Windhover, has risen dramatically
over the past three years. But
so has the value of non-cash components – marketing
carve-outs, co-promotions, development
direction. And many of these
deals are morphing into acquisitions
-- $12 billion worth of biotech acquisitions
in 2006, says Windhover, up by 20%
over the previous year, with twice
as many deals valued at greater than
$400 million. The driver: Big
Pharma’s pipeline drought. All
of which has increased the challenge
for Big Pharma’s dealmakers and
the opportunities for biotechs.
This panel will talk about those
challenges and opportunities: the
new trade-offs Big Pharma is being
forced to make (between internal
and external spending; between old
and new returns expectations); the
new strategies for risk sharing and
off-P&L financing; and fundamentally,
the sustainability of ever-more expensive
partnering in a high-infrastructure
industry . This session will
feature several of the most experienced
dealmakers from both Big Pharma and
biotech. |
|
|
|
|
|
13:30-18:15 |
| BUSINESS
DEVELOPMENT TRACK |
|
|
13:30-14:30 |
|
Moderator: |
Diane
Romza-Kutz, Member of the Firm, Health
Care and Life Sciences Practice, Epstein
Becker & Green P.C. |
| Panelists: |
| • |
Steven Damon,
VP, Business Development, Altea
Therapeutics |
| • |
Pamela Demain,
Executive Director, Corporate Licensing,
Merck & Co., Inc. |
| • |
Joseph
Dillon, Senior VP, Corporate Development
Services, The Mattson Jack Group |
| • |
Michele Garufi,
Chairman & CEO, NicOx SA |
| • |
Dr. Don Lucas,
Associate Director, Alliances,
Licensing, and Acquisitions, Procter & Gamble
Pharmaceuticals |
| |
|
|
| Abstract: |
The
trend has developed for biotech
companies to do deals among each
other in early-stage development
phases.
Even though these collaborations
can be very successful and
support company development
in its early years, their impact
goes beyond the early-stage
phase of companies.
Once companies increase in size,
their platform/products prove
to be promising and companies
start partnering with larger
multinationals for more global
deals, those early-stage collaborations
might pose obstacles to reach
the next milestone in a biotech’s
development.
How does Big Pharma view early-stage
deals? How can you best
structure those collaborations?
Where are mistakes most often
made and how do you avoid them?
This panel will provide an insight
on this topic from the eye of
Biotech as well as Big Pharma.
Major dealmakers from both sides
will shed light on the risks
and chances of doing Biotech
to Biotech early-stage deals.
Top
of Page |
|
|
|
14:45-15:45 |
|
Moderator: |
Dr.
Simba Gill, CEO, moksha8 and Venture
Partner, Entrepreneur in Residence, TPG
Growth |
| Panelists: |
| • |
Robert DeBenedetto,
VP Global Business Development,
NovaQuest, The Partnering Group
of Quintiles Transnational |
| • |
Dr. Ken Macleod,
Principal, Paul Capital Partners |
| • |
Gardiner Smith,
Advisor, SHI Link |
| • |
Dr.
Greg Wiederrecht, VP, External
Scientific Affairs, Merck & Co.,
Inc. |
| |
|
|
| Abstract: |
While
the U.S. and European drug development
markets remain dominant in terms
of size and number of companies,
the rest of the world is beginning
to catch up as investors and
biotech entrepreneurs are figuring
out how to leverage the cost
and regulatory advantages found
in emerging biotech hubs around
the world. The more innovative
companies are leaving the comfort
zone of keeping everything close
to home and are now looking for
discovery and development partners
in regions offering better service,
comparable or better science,
and more affordable prices. At
the same time, the larger regional
firms in Asia and other developing
markets are looking to assert
themselves globally by exploring
innovative partnerships and development
strategies to build value downstream
and access markets in the U.S.
and Europe. Drug discovery,
development, and distribution
are all now global activities
involving key stakeholders throughout
the world. This session
will examine new types of transactions
and alliances that seek to take
advantage of opportunities to
access capital, technology, markets,
and drug development expertise
on a global basis. Panelists
will discuss why and how they
have made these decisions to
look beyond the traditional options
for building companies and why
they believe this will increase
their prospects for success.
Top
of Page |
|
|
|
16:00-17:00 |
|
Moderator: |
Morrie
Ruffin, CEO, Life Tech Innovations, LLC |
| Panelists: |
| • |
Vincent Aurentz,
Senior Executive VP, Portfolio
Management and Business Development,
Merck Serono International SA |
| • |
Dr. Luca Bolliger,
Director Business Development,
Actelion Pharmaceuticals Ltd |
| • |
Gwen
Melincoff, VP Business Development,
Shire Pharmaceuticals Inc. |
| • |
Dr. Massimo Radaelli,
President and CEO, Dompé International
SA |
| |
|
|
| Abstract: |
The
recent wave of consolidation
across the European mid-size
pharma companies raises a number
of very important issues regarding
their potential role as development
partners for earlier stage companies.
While some “new” companies
are emerging with stronger portfolios
and expertise in specialty markets,
questions remain about their
ability to compete and bid for
assets going forward. At the
same time, earlier stage companies,
when considering their partnering
options, will have to weigh the
relative value of what may appear
to be a more “committed” partner
that may offer more downstream
potential to the increasingly
attractive deal economics offered
by the larger pharma firms. This
session will examine the decision
making process from both sides
of the table – how mid-size
pharma is approaching their in-licensing
strategies going forward and
how small-mid size biotech firms
are evaluating their options
when considering whether a mid-size
pharma partner is a better option
than selling out to the big guys.
Top
of Page |
|
|
|
17:15-18:15 |
|
Moderator: |
Martin
Austin, Managing Director,TransformRX |
| Panelists: |
| • |
François
Arcand, CEO, ERA Biotech, SA |
| • |
Camille Burel,
Industrial Biotech Project Administrator,
EuropaBio |
| • |
James
C. Greenwood, President & CEO,
Biotechnology Industry Organization
(BIO) |
| • |
Jack Grushcow,
President, Linnaeus Plant Sciences
Inc. |
| |
|
|
| Abstract: |
White,
or industrial, Biotech is usually
seen by the pharmaceutical industry
as having a role only as a means
of making savings through reductions
in manufacturing costs. Given
that cost of goods is a small
component of overall drug costs,
as yet, little attention has
been paid to new technologies
emerging from this new area.
However, White Biotechnology
is making great strides not
only in using bio-catalysis
as a means for major reductions
in the number of synthetic
steps required to create complex
compounds, it also produces
novel compound structures leading
to whole new libraries of products
to screen both against known
targets and those emerging
from genomic studies of disease.
This new and little explored
area will be a major source
of new products from Bio-Drug
Discovery methods. The panel
will discuss achievements to
date and breaking developments
in this exciting new field.
Top
of Page |
|
|
|
| |
|
13:30-18:15 |
|
13:30-14:30 |
Moderator: |
Vivian
Lee , Managing Director, Aqua Partners
LLC |
| Panelists: |
| • |
Dr.
Angeliki Kotsianti,
Director, Global Clinical
Technology, Pfizer
Human Health Technologies |
| • |
Dr.
Neill MacKenzie, Senior
VP, Business Development
and Commercial Strategy,
MediGene |
| • |
David
Muth, Executive VP
and CBO, Avalon Pharmaceuticals |
| • |
Prof.
Giorgio Parmiani, Unit
of Immuno/Biotherapy
of Solid Tumors, Department
of Oncology, San Raffaele
Scientific Institute,
Milano |
| |
|
|
| Abstract: |
Notwithstanding
tremendous strides made in the
laboratory, adoption of non-cytotoxics
such as monoclonal antibodies
and target-specific small molecules
has taken much longer than early
industry media hype suggested. In
2005, cytotoxic agents still
accounted for the bulk of the
$20 billion cancer therapeutics
market. But by 2010, sales
of drugs specific for genes,
proteins, proteosomes and intracellular
signaling pathways characteristic
of cancer are expected to overtake
that of conventional cytotoxic
and antihormonal therapies in
a market totaling an estimated
$31 billion.
This session
will explore the link between
cancer companies and the oncologists
who are the ultimate adopters
of their innovations. What
is the role of third party
payor reimbursement? What
are the expectations and concerns
facing clinicians and their
patients in the field today? How
are these reconciled with development
imperatives facing companies
ranging from big pharma to
emerging oncology specialty
firms?
Top
of Page |
|
|
|
14:45-15:45 |
Moderator: |
Mike
Ward, Senior Editor, BioCentury Publications
Inc. |
| Panelists: |
| • |
Dr.
Dominik Escher, CEO, ESBATech AG |
| • |
Dr. Kevin Johnson,
CEO, PanGenetics BV |
| • |
Evert Kueppers,
CEO, Pieris AG |
| • |
Dr.
Simon Moroney, CEO, MorphoSys AG |
| • |
Prof. Jan G.
J. van de Winkel, Executive VP & CSO,
Genmab A/S |
| |
|
|
| Abstract: |
Antibodies have
provided us with a successful therapeutic
class of drugs and although there are
drawbacks such as cost of production
and patient administration, the market
has grown rapidly in the recent years.
As technology has progressed, monoclonal
antibodies were reengineered to chimeric,
humanized and fully humanized versions
reducing immune responses and increasing
market potential. Traditional therapy
areas for antibodies are oncology and
autoimmune/inflammatory disorders, but
infectious and cardiovascular diseases
as well as ophthalmology also seem to
be benefiting from the high level of
innovation of antibody technology.
Copmanies are now turning their attention
to the next generation of antibody-based
therapeutics. Some pharma companies acquire
antibody and antibody fragment companies,
while others have signed deals worth
potentially hundreds of millions of dollars.
This session will explore the opportunities
and threats in the antibody space and
look at the key players in this market.
It will further examine which companies
are innovators and what the key attributes
of the next wave of antibody-like therapeutics
will be.
Top
of Page
|
|
|
16:00-17:00 |
Moderator: |
Dr.
Richard J. Hammel, Partner, Richard J.
Hammel, IBC, Inc. |
| Panelists: |
| • |
Dr. Cornelia
Blaettchen, Head of Business Development & Licensing,
Basilea Pharmaceutica Ltd. |
| • |
John Hollway,
VP, Business Development, Achaogen,
Inc. |
| • |
Dr. Praveen Tipirneni,
Head of Corporate and Business
Development, Cubist Pharmaceuticals |
| |
|
|
| Abstract: |
Infectious Diseases
represent an area of clear unmet high
medical need, not the least because
it appears that no matter what new
drugs are brought to the market, bacteria
keep one step ahead!
Many current treatments
can be effective, but with multiple
side effects. Moreover, drug developers
are also struggling with resistant
strains and bacteria adapting to
an ever-changing environment, an
additional challenge to bringing
effective drugs to the market.
Treatment of each
condition has its own challenges, ranging
from scientific to market dynamics.
This panel will explore the specific
challenges and hurdles that this therapeutic
area is facing. Panelists will also
try to identify market opportunities,
emerging trends and promising treatment
options and technologies.
Top
of Page |
|
|
17:15-18:15 |
Moderator: |
Dr.
Jesse Schulman, Director, Analysis & Research,
Ferghana Europe LLP |
| Panelists: |
| • |
Dr. Luca Benatti,
CEO, Newron Pharmaceuticals SpA |
| • |
Andy Brookes,
Senior. Director, Business Development,
Biogen Idec International GmbH |
| • |
Dr. Lubor
Gaal, Director, Licensing Europe,
Bristol-Myers Squibb |
| • |
Dr. John Kemp,
Chief Research & Development
Officer, Evotec AG |
| |
|
|
| Abstract: |
Disorders of the
Central Nervous System (CNS) are many,
varied and frequently severe, affecting
a large portion of the population.
These debilitating disorders include
diseases such as epilepsy and migraine;
degenerative conditions such as Parkinson's
disease; and psychiatric disorders
such as anxiety, bipolar disorder,
depression, and schizophrenia. In addition,
chronic pain is a neurological response
to disease or injury; or it may have
no readily apparent cause. Regardless
of its origins, pain can have devastating
effects on those suffering from it.
Progress towards
finding a cure for CNS disorders
has dramatically increased in the
past years as our understanding of
the brain and how disease affects
it has improved. Nevertheless, there
are still many conditions for which
treatment choices are limited, and
where drugs merely treat the symptoms
and do not provide cures.
The complexity of
the CNS makes it a challenging area
of research but of course also a very
rewarding space for the development
of new drugs.
Where are the clear
unmet medical needs in the CNS space?
Which specific areas look most exciting
today? What are the market opportunities
and what are the specific threats?
This session will identify market dynamics
and emerging technologies from a large
pharma and biotech perspective.
Top
of Page |
|
|
| |
|
13:30-18:15 |
|
13:30-14:15 |
| The Seminar is
an opportunity for the international business
community to get acquainted with leading-edge
Italian Biotech scientific achievements
and latest industry developments. Come and explore
a wide spectrum of collaborative prospects
ranging from research to co-development programs
and learn recent success stories pertaining
to Italian and foreign collaborations. |
| Agenda: |
| 13:30 |
Supporting
business development of biotech investors
in Italy
Roberto Spingardi – Head of Inward Investment,
InvestInItaly |
| 13:35 |
Industrial
impacts pertaining to HTPS of molecules
interfering with Embryonic Stem cell differentiation
Silvia Parisi – Senior Researcher, CEINGE – Biotecnologie
Avanzate |
| 13:45 |
Venturing
on a new frontier: genetic vaccines for
chronic diseases
Riccardo Cortese – President & CEO,
OKAIROS
|
| 13:55 |
An Italian
biotech success story
Luca Benatti – Managing Director & CEO,
Newron Pharmaceuticals |
| 14:05 |
The
emerging biotechnology in Italy - The arrival
of the bio renaissance
Byron Hewett – President & CEO,
Immunicon Corporation |
| 14:15 |
End
of Session |
| |
|
|
14:30-15:45 |
BLOSSOM ASSOCIATI - ASSOBIOTEC REPORT |
| |
|
| Welcome: |
Prof.
Leonardo Santi, President of the National
Committee for Biosafety, Biotechnology and
Life Sciences at the Presidency of
the Council of Ministers |
Chairman:
Dr.
Roberto Gradnik, President of
Assobiotec
Speakers:
Dr.
Massimo Boriero, Board of Directors,
Biotech Group of Farmindustria
Stefano
Milani,
Managing
Director
Blossom Associati,
Contract
Professor
at the University
of Pavia
Alberto
Onetti,
Professor
at the Insubria
State University
of Varese,
Director
Research
Centre for
Health Care
Management
and Innovation
(CrESIT)
Antonella
Zucchella,
Professor
at the University
of Pavia,
VP Center
for Innovation
and Technology
Transfer
ITT" University
of Pavia
Top of Page |
|
16:00-17:00 |
| | |